2016-06-08 Artykuł

Metabolic disturbances in autism

Prevalence of autistic spectrum disorders (ASD) increased dramatically in recent three decades, however, its etiology and epidemiology remains unsolved. It is suggested that about 75-80% of the tracked increase in autism since 1988 is due to an actual increase in the disorder rather than to changing diagnostic criteria. Over two hundred separate genetic loci are considered to play a role in ASD development, however a debate continues whether the disease is heritable. Many scientists agree that the interactions of environmental factors with gene susceptibilities in ASD have been relatively overlooked. Several biochemical and physiological disturbances are consistently associated with autism.

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Autor: prof. dr hab. Krzysztof L. Krzystyniak, dr n. med. Andrzej Marszałek, prof. dr hab. Mieczysław Obiedziński

Data publikacji: 2016-06-08

Źródło: Gabinet Prywatny 02/2016

Słowa kluczowe: autism, autism spectrum disorders (ASD), oxidative stress biomarkers, glutathione, thioredoxin, sulfate metabolism, vitamin D, serotonin, environmental toxicants, gut dysbiosis.

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